Wrinkle treatments

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Botox and filler applications, especially in the face of non-surgical applications outside the face. Botox and filler applications are different from each other, the effects and usage areas are different. Botox applications are effective especially in the 1/3 upper part of the face while filling applications are more effective in the 2/3 lower part of the face. In some cases, only botox or filler is not enough, it should be used at the same time or at short intervals.


Botox is a kind of toxin (poison) and is produced from bacteria living in the airless environment called clostridium botilinum. Disease caused by the ingestion of this bacterium is first described by poet Justinus Kerner in the 1800s.

During the economic troubles during Napoleonic wars, the disease caused by this bacterium is frequently encountered in the hygiene deficiencies of food production. This disease was frequently seen in sausage poisoning and the name botox came from botus (sausage). It has nothing to do with snake venom.

Botox is temporarily stopping the nerves and disease is seen. The botulinum toxin is heat sensitive and the effect of cooking is lost. Botulinum toxin is also used in the treatment of aesthetic surgery and some other diseases. Botilinum too high doses are needed to create the disease. For treatment and aesthetic purposes, the dose is very low and safe. It has been used safely in the treatment of diseases for many years.

It has been used mainly in the treatment of speech disorder called spasmotic dysphonia.

At the same time, blepharospasm (involuntary contraction of the eyelids), torticollis (shortness of the neck muscle), treatment of tics, strabismus treatment is used in the treatment of many other diseases.

In the 1990s botox began to be used in the treatment of facial wrinkles.

The mechanism of action of botox

Botulinum toxin acts on the nerves by stopping transmission.

Clinically the effect lasts for 2-6 months and then disappears. In total, harmful effects are generated at doses above 3000 units. However, the dose used for cosmetic purposes is about 100 units. Botulinum toxin (botox) is available in sterile and frozen form as Botulinum toxin type A.

In 1989, the US Food and Drug Administration (FDA) was approved. The most well-known botulinum toxin is found under the brands Botox and Dysport. These two products contain Botulinum toxin A.

Botulinum toxin should be stored frozen and stored at -5 ° C. In the hot environment, it begins to lose its effect. It is used by diluting with serum and should be used within 4 hours after reconstitution. In 12 hours the effect is halved.

Use of botulinum toxin for cosmetic purposes:

Sun damage, gravity effect, facial wrinkles with the effect of mimic muscles. Wrinkles due to movement of mimic muscles can be reduced or completely eliminated with Botulinum toxin. After administration of botulinum toxin, the effect usually begins within 1-3 days. It is maximized within 1-2 weeks. A slight bruising may occur at the site of botulinum toxin. It is appropriate not to use aspirin and similar drugs 10-14 days prior to injection. Botulinum toxin effect continues for 3-6 months.

Botox use in forehead wrinkles

The use of botulinum toxin (botox) in forehead wrinkles gives very good results. This region is lost in the lines formed between the eyebrows.

The forehead muscle (frontal muscle) is used to lift the eyebrows and eyebrows upward. Therefore over-made botulinum toxin (botox) may cause it to fall on the eyebrows. For this reason, injection points of Botulinum toxin are determined from bottom to top in the form of inj V al.

If wrinkles are moving towards the temple area, Botulinum toxin (botox) is applied to the sides in a controlled manner. However, it should not be done outside the eye level otherwise the chewing muscles are weakened. It is necessary not to go to bed for 2-3 hours after the application of the tubulinum toxin, thus preventing the distribution of Botulinum toxin elsewhere.

Botulinum toxin (botox) is the most common place of application. There are 4 basic muscles in this area that cause wrinkle formation. The muscle called the Korugator functions to pull the inner parts of the eyebrow in the midline and downward direction. Usually 5 different points are injected in this region.

Before the injection, the patient is asked to scratch his / her eyebrows and the placement of the muscle is determined. 2.5-5 unit dose was effective in the studies and 10-20 units were sufficient for this region. Botulinum toxin (botox) applications are quite effective in this region, but this activity is reduced in individuals with thick and oily skin.

Botox around the eyes (crow’s feet) wrinkles

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